Which symptom indicates a possible addiction to opioids in long-term users?

In long-term users of opioids, increased tolerance to the drug is a significant symptom that may indicate an addiction. Tolerance develops when a person requires larger doses of a substance to achieve the same effects that were once felt with smaller amounts. This is a common consequence of prolonged use of opioids, as the body adjusts to the drug’s presence and its effects diminish over time.

When individuals find that they need to take higher doses to relieve pain or achieve the desired euphoric effect, it can signify a dependency and an increased risk of addiction. This symptom is particularly important to monitor because it can lead to escalating use, increased side effects, and a higher likelihood of experiencing overdose.

The other options do not indicate addiction. Improved cognitive function and heightened energy levels are not typically associated with opioid use, which often leads to sedation and cognitive impairment. Lowered blood pressure can be a side effect of opioids but is not a clear indicator of addiction. Therefore, increased tolerance is a key sign to look out for when assessing the potential for opioid addiction in long-term users.